Browsing by Author "Hatipoğlu, İbrahim"
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Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
Çalışkan, Figen; Ergene, Emel; Sögüt, İbrahim; Hatipoğlu, İbrahim; Basalp, Aynur; Sivas, Hülya; Kanbak, Güngör (Pergamon-Elsevier Science LTD, 2013)Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ... -
Effects of fibronectin and type IV collagen on osteosarcoma cell apoptosis
Seller, Zerrin; Hatipoğlu, İbrahim; Sivas, Hülya; Ergene, Emel; Çiftçi, Gülsen Akalın (Natl Inst Science Communication-Niscair, 2013)The aims of this study are the investigation of the effects of fibronectin and type IV collagen extracellular matrix proteins and the role of caspase-3 and -9 on cis-platin induced U2-OS apoptosis were studied. First the ... -
Hepatit B aşısı geliştirme ve Hepatit B aşılarının etkinliğini artırmaya yönelik yaklaşımlar
Hatipoğlu, İbrahim (Anadolu Üniversitesi, 2012)Hepatit B Virüsü (HBV) enfeksiyonu dünya genelinde önemli bir sağlık sorunudur. Dünya Sağlık Örgütünün verilerine göre dünya nüfusunun üçte biri bu virüs ile enfektedir, yaklaşık 370 milyon kişi ise kronik hepatit B ... -
Ras aktif hücrelerde kaspazların apoptoz üzerine etkileri
Hatipoğlu, İbrahim (Anadolu Üniversitesi, 2006)Bu tez kapsamında, Cis-platin ile stimüle edilen insan-U20S (osteosarkoma) hücrelerindeki morfolojik ve biyokimyasal değişimler, kaspaz-3 ve kaspaz-9 enzimlerinin apoptotik mekanizma üzerine etkileri incelenmiştir. Bunun ... -
Stimulation of dendritic cells with vaccine and vaccine-antibody complex and effect on immune response
Hatipoğlu, İbrahim; Sögüt, İbrahim; Ercan, Duygu; Aksu, SÖner; Sivas, Hülya; Basalp, Aynur (Tubitak Scientific & Technical Research Council Turkey, 2013)Dendritic cell (DC) vaccines are a promising and potent therapeutic tool for chronic diseases, autoimmune diseases, and cancer because of the unique ability of DCs to stimulate T cells. The challenge of DC vaccines is to ... -
Stimulation of dendritic cells with vaccine and vaccine–antibody complex and effect on immune response
Dendritic cell (DC) vaccines are a promising and potent therapeutic tool for chronic diseases, autoimmune diseases, and cancer because of the unique ability of DCs to stimulate T cells. The challenge of DC vaccines is to ... -
Synthesis of some 3,4-disubstituted-6,7-dihydro-imidazo[2,1-b][1,3]thiazole and 3,4-disubstituted-7,8-dihydro-6H-imidazo[2,1-b][1,3]thiazine derivatives and evaluation of their cytotoxicities against F2408 and 5RP7 cells
Meriç, Asiye; Seller, Zerrin; Hatipoğlu, İbrahim (Birkhauser Boston Inc, 2008)This article describes the synthesis of 3,4-disubstituted-6,7-dihydro-imidazo[2,1-b][1,3]thiazoles and 3,4-disubstituted-7,8-dihydro-6H-imidazo[2,1-b][1,3]thiazines, having substituted or nonsubstituted phenyl rings at the ...